Your evidence-based guide to HPV vaccination and cervical cancer prevention
Science Vs Social Media – Episode 03
The HPV vaccine in India is one of the most effective ways to prevent cervical cancer.
India accounts for 25% of global cervical cancer deaths. One in every five women globally who suffers from cervical cancer is from India. India ranks fourth globally in cervical cancer-related morbidity.
HPV is a virus called Human Papillomavirus. And the vaccine is called the HPV Vaccine. Since this infection is mostly preventable, the HPV vaccine can be very helpful in the prevention of this disease.
Still, many questions and myths surround this conversation. Like, is it only for teenagers? Is it safe? What vaccines are available in India? Does it cause infertility?
💡Quick Facts
First things first – What is HPV?
As said earlier, it is a virus called Human Papillomavirus. It is a very common virus spread through close skin-to-skin contact. There are over 200 types of HPV, and about 40 of them can infect the genital area.
One thing that often surprises people is that not all HPV types are the same. Think of HPV as a large family with over 200 relatives. Some members of the family are relatively harmless, while a few are known troublemakers. To make things easier, doctors broadly classify HPV into two groups:
Low-risk HPV: These types are unlikely to cause cancer but can cause genital warts and rarely lead to cancer. HPV types 6 and 11 account for nearly 90% of genital wart cases.
High-risk HPV: These are the types that require more attention. If the infection persists for several years, they can cause changes in cells that may eventually lead to cancer.
HPV types 16 and 18 cause about 70% of cervical cancers worldwide. Other high-risk types can also lead to cancers of the vulva, anus, penis, and the back of the throat.

In most people, HPV is short-lived. The immune system quietly clears the infection without causing any symptoms, and many people never even realise they were infected. Problems arise only when certain high-risk HPV infections persist for years.
How Does HPV Spread?
One of the biggest misconceptions about HPV is that it spreads only through sexual intercourse.
In reality, the virus is transmitted through sexual intercourse. In reality, the virus is transmitted through intimate skin-to-skin contact, which means penetration is not necessary for infection to occur.
One can acquire HPV through:
- Vaginal sex
- Anal sex
- Oral sex
- Genital skin-to-skin contact
Because HPV infects the skin around the genitals, condoms lower the risk of spreading it but do not fully prevent it. Many people with HPV have no symptoms and can pass the virus to others without knowing.
Why Does HPV Matter?
HPV causes almost all cases of cervical cancer, which is a major cause of cancer deaths in women around the world.
Persistent HPV infection has also been connected to :
- Cervical cancer
- Vaginal cancer
- Vulvar cancer
- Anal cancer
- Oropharyngeal (throat ) cancers
- Genital warts
How Does the HPV Vaccine in India Work?
Think of the HPV vaccine as giving your immune system a “practice run.” It teaches your body to recognise specific HPV types before you’re ever exposed to them, allowing it to respond quickly if you encounter the virus in the future.
The vaccine prevents HPV infection but does not treat an existing infection or cure HPV-related diseases. This is why getting vaccinated before being exposed to the virus works best.
Research shows that HPV vaccination greatly lowers the rates of HPV infections, cervical precancers, genital warts, and cervical cancer in people who get the vaccine.
HPV Vaccines in India : Available Option
There are several approved HPV vaccines in India. They protect against different numbers of HPV types, but all of them work well to prevent HPV-related diseases.
| Vaccine | Manufacturer | HPV Types Covered | Available in India |
| Cervavac® | Serum Institute of India | 6, 11, 16, and 18 | Yes |
| Gardasil® | MSD (Merck) | 6, 11, 16, and 18 | Yes |
| Gardasil® 9 | MSD (Merck) | 6, 11, 16, 18, 31, 33, 45, 52, and 58 | Yes |
Note: The choice of vaccine depends on age, availability, and your healthcare provider’s recommendation.
What is Cervavac?
Cervavac is the first HPV vaccine developed in India. Developed by the Serum Institute of India, it was designed to make HPV vaccination more affordable and widely available while remaining safe and effective.
Which Vaccine Should You Choose?
All approved HPV vaccines protect well against the main cancer-causing types of HPV.
Gardasil 9 protects against more HPV types because it covers five extra high-risk types. Still, it is better to get any approved HPV vaccine than to wait while choosing between brands. Your doctor can help you pick the right vaccine for you based on your age, what is available, and your health history.
Who Should Get the HPV Vaccine in India?
Children (9–14 years)
This age is best for HPV vaccination because the immune system responds strongest before any exposure to HPV.
Most children in this age group require two doses, given six to twelve months apart.
Adolescents and Young Adults (15–26 years)
If you did not get the vaccine earlier, it is still strongly recommended. Even if you have been exposed to HPV, you probably have not come into contact with every type the vaccine protects against.
Most people aged 15 years and older require three doses.
Adults (27–45 years)
Adults aged 27 to 45 can still benefit from the vaccine, but the benefit is usually smaller since people are more likely to have already been exposed to HPV as they get older.
The decision should be based on a discussion with your healthcare provider, considering your health history, future risk of exposure, and personal preferences.

HPV Vaccine Schedule
The recommended schedule depends on the age at which vaccination begins.
- Ages 9–14 years: Two doses, six to twelve months apart.
- Age 15 years and above: Three doses, usually given at 0, 1–2, and 6 months.
- Immunocompromised individuals: Three-dose schedule regardless of age.
It is important to complete the recommended series to achieve optimal protection.
Science vs Social Media

Health information spreads quickly on social media, but not everything you see is true. Personal stories can be helpful, but vaccination decisions based on strong scientific evidence, not viral posts or rumours.If you’ve ever wondered whether you really need to “balance your hormones” or whether seed cycling works, we’ve explored those claims in our Science vs Social Media series.
Myth: “The HPV vaccine causes infertility.”
Science says: There is no credible scientific evidence that HPV vaccines cause infertility. Large studies involving millions of people have found no association between HPV vaccination and reduced fertility. In fact, preventing HPV-related cervical disease may reduce the need for treatments that can affect future pregnancies.
Myth: “I’m already married, so there’s no point getting vaccinated.”
Science says: This is false. Even if you have been sexually active, you are unlikely to have been exposed to every HPV type covered by the vaccine. Vaccination may still protect against future infections with HPV strains you have not encountered. The decision should be made in consultation with your healthcare provider.
Myth: “The HPV vaccine encourages teenagers to become sexually active.”
Science says: Multiple studies have shown that receiving the HPV vaccine does not increase sexual activity or risky sexual behaviour. The vaccine is recommended at a younger age because it produces the strongest immune response before exposure to HPV.
Myth: “Only girls need the HPV vaccine.”
Science says: HPV affects both women and men. It can cause genital warts and several cancers, including anal, penile, and throat cancers. Vaccinating eligible boys and girls helps reduce the spread of HPV and protects the wider community.
Myth: “The HPV vaccine isn’t safe.”
Science says: HPV vaccines have been used worldwide for nearly two decades and have an excellent safety record. Hundreds of millions of doses have been administered globally, and continuous safety monitoring has consistently shown that serious side effects are extremely rare.
Myth: “If I’m vaccinated, I don’t need a Pap smear.”
Science says: False. While the vaccine protects against the HPV types responsible for most cervical cancers, it does not cover every cancer-causing strain. Regular cervical cancer screening remains essential, even after vaccination.
Is the HPV Vaccine in India Safe?
Yes. The HPV vaccine has one of the strongest safety records among modern vaccines.
Before approval, it underwent extensive clinical trials involving thousands of participants. Since then, hundreds of millions of doses have been administered worldwide, and vaccine safety continues to be monitored by health authorities.
Most side effects are mild and temporary, including:
- Pain, redness, or swelling at the injection site
- Mild fever
- Headache
- Fatigue
- Muscle aches
Some teenagers may faint for a short time after getting the vaccine. That is why doctors usually ask you to sit and wait for about 15 minutes after the shot.
Serious side effects are very rare, and the benefits of preventing HPV-related cancers are much greater than the small risk of side effects.
Does the HPV Vaccine Replace Cervical Cancer Screening?
No.
HPV vaccination and cervical cancer screening work together—they are not substitutes for one another.
The vaccine lowers the risk of getting the most common cancer-causing HPV types, but it does not remove the risk completely. Regular screening can find abnormal cervical cells early, often before they turn into cancer.
Depending on your age and local guidelines, your healthcare provider may recommend:
- Pap smear (cervical cytology)
- HPV DNA testing
- Co-testing (Pap smear and HPV test)
Even if you have finished the HPV vaccine series, keep getting regular cervical cancer screenings as your doctor recommends.
HPV Vaccine During Pregnancy and Breastfeeding
The HPV vaccine is not recommended during pregnancy. If a woman becomes pregnant after starting the vaccine series, the remaining doses should simply be postponed until after delivery. There is no evidence that the vaccine harms the developing baby.
The vaccine is considered safe during breastfeeding, and eligible women can receive it without interrupting breastfeeding.
Frequently Asked Questions
Yes.
A common myth is that you do not need the HPV vaccine after getting married or becoming sexually active.
Although the vaccine works best before exposure to HPV, many adults have not encountered every HPV type covered by the vaccine. Vaccination may still provide protection against future infections with HPV strains you have not yet acquired.
Being married does not eliminate the potential benefits of vaccination.
Yes.
Women in their 30s and even early 40s may still benefit from HPV vaccination depending on their individual circumstances.
The decision depends on several factors, including previous HPV exposure, future risk of infection, and medical advice. Your healthcare provider can help determine whether vaccination is appropriate for you.
Yes. The vaccine does not treat an existing HPV infection, but it can still protect you against other HPV types included in the vaccine that you have not been exposed to.
Routine vaccination is recommended through age 26. Adults aged 27–45 years may still benefit, depending on individual circumstances, and should discuss vaccination with their healthcare provider.
Both are approved and effective vaccines.
Cervavac protects against four important HPV types (6, 11, 16, and 18) and is India’s first indigenously developed HPV vaccine.
Gardasil 9 provides broader protection by covering five additional high-risk HPV types linked to cervical cancer.
The best vaccine is the one that is available, suits your age, and is recommended by your doctor. It is usually better not to delay vaccination while choosing between brands.
No. It protects against the HPV types responsible for the majority of cervical cancers but not every cancer-causing HPV strain. This is why regular cervical cancer screening remains important.
Current evidence shows that HPV vaccines provide long-lasting protection for many years, with no indication that routine booster doses are currently needed.
Yes. If you could not finish or start the vaccine during pregnancy, you can get it after your baby is born. The vaccine is also safe while breastfeeding.
💜 What Would I Tell My Sister?
If my younger sister asked me whether she should get the HPV vaccine, I wouldn’t start by quoting research papers or statistics. I’d simply tell her this: if there’s a safe and effective way to reduce the risk of cervical cancer, it’s worth learning about. I’d encourage her to speak with her doctor, ask questions, and make an informed decision based on science, not social media or fear. Prevention isn’t about living in worry; it’s about giving yourself the best chance of a healthier future.
Key Takeaways
This article is for education only and is not a substitute for professional medical advice, diagnosis, or treatment. Vaccine recommendations can change based on your age, health history, and local guidelines. Always talk to a qualified healthcare professional before making decisions about HPV vaccination or cervical cancer screening.
References
- Ministry of Health & Family Welfare, Government of India.
HPV Vaccination Programme
https://www.pib.gov.in/PressReleasePage.aspx?PRID=2234009 - Serum Institute of India.
CERVAVAC® Product Information
https://www.seruminstitute.com/product_ind_cervavac.php - Indian Journal of Medical Research (IJMR).
Human papillomavirus vaccine for cancer cervix prevention: Rationale & recommendations for implementation in India
https://ijmr.org.in/human-papillomavirus-vaccine-for-cancer-cervix-prevention-rationale-recommendations-for-implementation-in-india/ - Indian Association of Preventive & Social Medicine (IAPSM).
Position Paper on Human Papillomavirus (HPV) Vaccination
https://pmc.ncbi.nlm.nih.gov/articles/PMC11927823/ - Foundation for Oncology and Gynecological Society of India (FOGSI).
Preventing Cervical Cancer through HPV Vaccination in India
https://www.fogsi.org/wp-content/uploads/2024/07/HPV-VACCINATION-1.pdf - Cancer Foundation of India.
Cervical Cancer Prevention & HPV Vaccination
https://cancerindia.org.in/cervical-cancer/ - World Health Organization (WHO).
Human Papillomavirus (HPV) and Cervical Cancer
https://www.who.int/news-room/fact-sheets/detail/human-papillomavirus-(hpv)-and-cervical-cancer
Research Papers
- Lei J, et al. HPV Vaccination and the Risk of Invasive Cervical Cancer. New England Journal of Medicine.
https://www.nejm.org/doi/full/10.1056/NEJMoa1917338 - Drolet M, et al. Population-level impact and herd effects following HPV vaccination programmes. The Lancet.
https://doi.org/10.1016/S0140-6736(19)30298-3














